Lupus and fibromyalgia are rheumatic disorders that share some symptoms and can be experienced concurrently by patients. Despite this overlap, lupus and fibromyalgia are distinct conditions that every patient will experience in his or her own way. In cases of lupus, the patient’s tissues, joints, and organs are attacked by the immune system. Fibromyalgia sufferers may manifest some symptoms similar to those associated with lupus but without experiencing inflammation, joint, or organ damage or many of the other complications that result from lupus, including a vulnerability to other infections such as colds, shingles, and pneumonia.Lupus and fibromyalgia are both chronic disorders, but the latter does not cause inflammation or organ and tissue damage. Fibromyalgia is generally characterized by widespread muscle, tendon, and ligament pain, as well as specific tender points and fatigue. In contrast to lupus, fibromyalgia is not progressive and does not make the patient vulnerable to other medical problems or diseases.